Orion™ Applications

Translating spatial biomarkers
into clinical impact

Spatial proteomics for precision therapeutics

Orion uniquely resolves tissue microenvironments at scale, and is routinely used to develop spatial biomarkers that measure response to therapy and for unlocking mechanistic, prognostic and predictive value for patient care.

Lab working with an Orion imaging instrument

Response to therapy. Predictive and prognostic biomarkers.

Cohort study
17-plex panel
Pre/post treatment
Survival probability

Measure response to therapy in clinical trials

Develop predictive panels for stratification

Perform drug target expression profiling

Uncover prognostic markers tied to clinical outcomes

Biomarker discovery and validation

2x4 tissue images
17-plex panel image

Protein validation of biomarkers downstream of transcriptomics

Immune profiling of host response to treatment or transplant

Determination of single-round high-plex panel for clinical applications

Orion - One platform for translational and clinical research

Scalable platform supporting biomarker development from validation through clinical trials

  • Extensive biomarker portfolio spanning a wide range of tissues and indications
  • Panel design is flexible, panel development is rapid, panel performance is reproducible
  • Biomarker depth, sample throughput, high-capacity workflow, and run costs designed for large cohort studies
  • Quantitative results built on a foundation of high-quality data

Any Tissue. Any Indication. 20 Channels in a Single Round.

Explore Tissue Atlas

Webinars

Jennifer Bordeaux, PhD

Spatial Biomarker Panels for Clinical Trials

Jennifer Bordeaux, PhD
Associate Director, Digital Pathology Services, Navigate Biopharma Services, Inc.

Watch the webinar →
Zhihong Chen

Bridging the Discovery-to-Translational Gap in Spatial Biology

Zhihong Chen, PhD
CTO, OCCAM Immune, Icahn School of Medicine, Mount Sinai Hospita

Watch the webinar →
Yana Zavros

Exploring new frontiers in pancreatic cancer treatment with spatial biology

Yana Zavros, PhD
Professor, University of Georgia School of Medicine

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Get started with Orion

Talk to a specialist about how Orion can accelerate your spatial biomarker program.

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